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Article

Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1.

Cancer letters - 1 Mar 2016

Seol Hyang Sook, Lee Sang Eun, Song Joon Seon, Rhee Je-Keun, Singh Shree Ram, Chang Suhwan, Jang Se Jin

Abstract excerpt

Tumor-initiating cells are important for the formation and maintenance of tumor bulks in various tumors. To identify surface markers of liver tumor-initiating cells, we performed primary tumorsphere culture and analyzed the expression of cluster of differentiation (CD) antigen genes using NanoString. Interestingly, we found significant upregulation of the complement proteins (p = 1.60 × 10(-18)), including C7 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26723877
DOI: 10.1016/j.canlet.2015.12.005
PMCID: PMC4744505

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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