Association of Tissue Inhibitor of Metalloproteinase-1 Genotypes with Lung Cancer Risk in Taiwan.

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Article

Association of Tissue Inhibitor of Metalloproteinase-1 Genotypes with Lung Cancer Risk in Taiwan.

Anticancer research - 1 Jan 2016

Lai Chung-Yu, Chang Wen-Shin, Hsieh Yi-Hsien, Hsu Chin-Mu, Tsai Chia-Wen, Chen An-Chyi, Wang Chung-Hsing, Bau Da-Tian

Abstract excerpt

AIM: Tissue inhibitors of metalloproteinases (TIMPs) are a family of multifunctional proteins whose expression has been shown to be up-regulated in various types of cancer. However, the contribution of TIMPs to lung cancer is not known. The present study aimed to evaluate the contribution of TIMP1 rs4898, rs6609533 and rs2070584 genetic polymorphisms to the risk of lung cancer. MATERIALS AND METHODS: The...

Topics

Aged
Biomarkers, Tumor
Case-Control Studies
Chi-Square Distribution
Female
Gene Frequency
Genetic Association Studies

Source

Open in PubMed

Identifiers

PMID: 26722039

Genes

TIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Humans

Logistic Models

Lung Neoplasms

Male

Middle Aged

Odds Ratio

Phenotype

Pilot Projects

Polymorphism, Genetic

Risk Assessment