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Article

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration

30 Dec 2015

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD), the most common cause of incurable blindness in the western world, is characterized by the dysfunction and eventual death of choroidal endothelial (CECs), RPE, and photoreceptor cells. Stem cell-based treatment strategies designed to replace photoreceptor and RPE cells currently are a major scientific focus. However, the success of these approaches likely also will...

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PMID: 26720480
DOI: 10.1167/iovs.15-17073

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