Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preclinical Models for Studying Fuchs Endothelial Corneal Dystrophy

28 Mar 2025

Abstract excerpt

Fuchs Endothelial Corneal Dystrophy (FECD) is a corneal endothelial disease that causes microenvironment alterations and endothelial cell loss, which leads to vision impairment. It has a high global prevalence, especially in elderly populations. FECD is also one of the leading indications of corneal transplantation globally. Currently, there is no clearly defined canonical pathway for this disease, and it has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal surgery and disorders
Share to Corneal Surgery and Treatments
Share to Glaucoma and retinal disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40214459
DOI: 10.3390/cells14070505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preclinical Models for Studying Fuchs Endothelial Corneal DystrophyPMID 40214459Read ↗

Fuchs endothelial corneal dystrophy: current perspectivesSemantic proximity Read ↗

Endoplasmic Reticulum-Mitochondria Crosstalk in Fuchs Endothelial Corneal Dystrophy: Current Status and Future ProspectsSemantic proximity Read ↗

Fuchs endothelial corneal dystrophy: current perspectives on diagnostic pathology and genetics—Bowman Club LectureSemantic proximity Read ↗

Fuchs Endothelial Cornea Dystrophy: A Review of the Genetics Behind Disease DevelopmentSemantic proximity Read ↗

Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophySemantic proximity Read ↗

Proteasomal Dysfunction results in ER stress, Endo MT, oxidative stress, and apoptotic cell death resulting in Fuchs Corneal Endothelial Dystrophy like features in miceSemantic proximity Read ↗

Characterization of a novel mouse model for Fuchs Endothelial Corneal DystrophySemantic proximity Read ↗

Mitochondrial Dysfunction and Mitophagy in Fuchs Endothelial Corneal DystrophySemantic proximity Read ↗

Early Transcriptomic and Pathologic Changes of Col8a2 Mutant Fuchs Endothelial Corneal Dystrophy.Semantic proximity Read ↗

Heterogeneity of human corneal endothelium implicates lncRNA NEAT1 in Fuchs endothelial corneal dystrophySemantic proximity Read ↗

RNA-Seq–based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophySemantic proximity Read ↗

RNA-Seq–Based Transcriptome Analysis of Corneal Endothelial Cells Derived from Patients with Fuchs Endothelial Corneal DystrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.