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Article

Oxidized low-density lipoprotein upregulates microRNA-146a via JNK and NF-κB signaling.

Molecular medicine reports - 1 Feb 2016

Li Zhenwei, Wang Shuai, Zhao Wenting, Sun Zewei, Yan Hui, Zhu Jianhua

Abstract excerpt

Increasing evidence suggested the involvement of microRNA (miR)-146a in the pathogenesis of multiple diseases, including atherosclerosis, bacterial infection and cancer. However, the mechanism by which miR-146a is regulated in macrophages exposed to oxidized low-density lipoprotein (oxLDL) has remained elusive. The present study aimed to explore the molecular pathway of miR-146a regulation in response to oxLDL....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26718614
DOI: 10.3892/mmr.2015.4729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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