Article
MiR-140a contributes to the pro-atherosclerotic phenotype of macrophages by downregulating interleukin-10.
European review for medical and pharmacological sciences - 1 Sept 2020
Yang H-X, Jiang H-B, Luo L
Abstract excerpt
OBJECTIVE: The dysfunction of immune cells plays important roles in promoting the progression of atherosclerosis (AS). This study aims to investigate the role of miR-140a in modulating the function of AS-associated macrophages. PATIENTS AND METHODS: The expression of miR-140a in human monocytes was evaluated by quantitative PCR. For in vitro studies, macrophages were transfected with miR140a mimic or miR140a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
