Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase.

BMC medical genetics - 28 Jul 2017

Wang Shuo, Song Jieyun, Yang Yide, Zhang Yining, Chawla Nitesh V, Ma Jun, Wang Haijun

Abstract excerpt

BACKGROUND: Hypoxia Inducible Factor 3 Alpha Subunit (HIF3A) DNA has been demonstrated to be associated with obesity in the methylation level, and it also has a Body Mass Index (BMI)-independent association with plasma alanine aminotransferase (ALT). However, the relation among obesity, plasma ALT, HIF3A polymorphism and methylation remains unclear. This study aims to identify the association between HIF3A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine Transaminase
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Basic Helix-Loop-Helix Transcription Factors

Share to Body Mass Index

Share to DNA Methylation

Share to Obesity

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28754107
DOI: 10.1186/s12881-017-0437-0
PMCID: PMC5534125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase.PMID 28754107Read ↗

HIF3A DNA Methylation Is Associated with Childhood Obesity and ALTSemantic proximity Read ↗

The HIF1α polymorphism rs2301104 is associated with obesity and obesity-related cytokines in Han Chinese population.Semantic proximity Read ↗

Association between the extent of DNA methylation at the CpG sites of <i>HIF3A</i> and parameters of obesity in the general Japanese populationSemantic proximity Read ↗

DNA Methylation Variants at HIF3A Locus, B-Vitamin Intake, and Long-term Weight Change: Gene-Diet Interactions in Two U.S. Cohorts.Semantic proximity Read ↗

IRX3 is a genetic modifier for birth weight, adolescent obesity and transaminase metabolism.Semantic proximity Read ↗

Effect of obesity on the association between ATF3 gene haplotypes and C-reactive protein level in Taiwanese.Semantic proximity Read ↗

Increased Methylation of Interleukin 6 Gene Is Associated with Obesity in Korean WomenSemantic proximity Read ↗

Associations of I148M variant in PNPLA3 gene with plasma ALT levels during 2-year follow-up in normal weight and overweight children: the PANIC Study.Semantic proximity Read ↗

Association of LXRα polymorphisms with obesity and obesity-related phenotypes in an Iranian population.Semantic proximity Read ↗

Association between hypoxia-inducible factor-1 alpha rs11549465 (1772 C>T) polymorphism and metabolic syndrome.Semantic proximity Read ↗

Genetic Variation in NFKB1 Gene Influences Liver Enzyme Levels in Morbidly Obese Women.Semantic proximity Read ↗

Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT 5-8 and -173 G>C): relationship with mRNA expression and soluble MIF levels in young obese subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.