Article
ADRB3 gene promoter DNA methylation in blood and visceral adipose tissue is associated with metabolic disturbances in men.
Epigenomics - 1 Feb 2014
Guay Simon-Pierre, Brisson Diane, Lamarche Benoit, Biron Simon, Lescelleur Odette, Biertho Laurent, Marceau Simon, Vohl Marie-Claude, Gaudet Daniel, Bouchard Luigi
Abstract excerpt
AIM: ADRB3 DNA hypermethylation was recently associated with dyslipidemia in familial hypercholesterolemia (FH). In this study, we verified whether ADRB3 DNA methylation in blood and visceral adipose tissue (VAT) was associated with obesity and its related complications. METHODS: DNA methylation levels were measured in the blood of 61 FH men, and the blood and VAT of 30 severely obese men. Common ADRB3...
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