Article
Analysis of estrogen receptor (ERalpha and ERbeta) and progesterone receptor (PR) polymorphisms in uterine leiomyomas.
Medical science monitor : international medical journal of experimental and clinical research - 1 Jan 2003
Massart Francesco, Becherini Lucia, Marini Francesca, Noci Ivo, Piciocchi Luigi, Del Monte Francesca, Masi Laura, Falchetti Alberto, Tanini Annalisa, Scarselli Gianfranco, Brandi Luisa
Abstract excerpt
BACKGROUND: Leiomyomas are the most common tumors in women, found in up to 30% of women in active reproductive life. These tumors are estrogen- and progestin-responsive. In fact, they do not occur before menarche, undergoing rapid increase in size during pregnancy with consequent fetal wastage. Conversely, they can regress or even calcify after menopause or castration. Given the central role of sex steroids in...
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