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Article

Salt-sensitivity of σ(H) and Spo0A prevents sporulation of Bacillus subtilis at high osmolarity avoiding death during cellular differentiation.

Molecular microbiology - 1 Apr 2016

Widderich Nils, Rodrigues Christopher D A, Commichau Fabian M, Fischer Kathleen E, Ramirez-Guadiana Fernando H, Rudner David Z, Bremer Erhard

Abstract excerpt

The spore-forming bacterium Bacillus subtilis frequently experiences high osmolarity as a result of desiccation in the soil. The formation of a highly desiccation-resistant endospore might serve as a logical osmostress escape route when vegetative growth is no longer possible. However, sporulation efficiency drastically decreases concomitant with an increase in the external salinity. Fluorescence microscopy of...

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Identifiers

PMID: 26712348
DOI: 10.1111/mmi.13304
PMCID: PMC4992981

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Source receipt: pubmed, retrieved 7 Sept 2026.

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