Article
β-Thalassemia Haplotypes in Romania in the Context of Genetic Mixing in the Mediterranean Area.
Hemoglobin - 1 Jan 2016
Cherry Laudy, Calo Carla, Talmaci Rodica, Perrin Pascale, Gavrila Lucian
Abstract excerpt
The purpose of this meta-study was to investigate β-thalassemia (β-thal) mutations and their chromosomal background in order to highlight the origin and spread of thalassemia alleles in the European and Mediterranean areas. Screening of more than 100 new Romanian β-thal alleles was also conducted...
Topics
- Alleles
- Amino Acid Substitution
- Codon
- Gene Frequency
- Haplotypes
- Humans
- Linkage Disequilibrium
- Mutation
- Polymorphism, Restriction Fragment Length
- Romania
- beta-Globins
- beta-Thalassemia