Article
Two new β+ -thalassemia mutation [β -56 (G → C); HBBc. -106 G → C] and [β -83 (G → A); HBBc. -133 G → A] described among the Tunisian population.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Douzi Kais, Moumni Imen, Zorai Amine, Ben Mustapha Maha, Ben Mansour Ikbel Mosbahi, Dorra Chaouachi, Salem Abbes
Abstract excerpt
OBJECTIVES: Different thalassemia mutations have been reported in various ethnic groups and geographical regions in Tunisia. In the present study, we have investigated two rare β(+) -thalassemia mutations, that have not previously been reported in the Tunisian population [β -56 (G > C); HBBc. -106 G > C] and [β -83 (G > A); HBBc. -133 G > A]. METHODS: The whole β-globin gene was directly sequenced, and haplotype...
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