Article
The Spectrum of β-Thalassemia Mutations in the Population Migration in Lebanon: A 6-Year Retrospective Study.
Hemoglobin - 1 Nov 2021
Farra Chantal, Abdouni Lina, Souaid Mirna, Awwad Johnny, Yazbeck Nadine, Abboud Miguel
Abstract excerpt
β-Thalassemia (β-thal) is highly prevalent among the Mediterranean populations. In Lebanon, the carrier rate of the disease is estimated to be around 2.0-3.0%. In this retrospective study, we determined the spectrum of β-thal mutations in a total of 170 individuals from a sample of 140 Lebanese, Iraqi and Syrian refugee families in Lebanon, over a period from 2012 to 2018. Twenty-eight different β-globin gene...
Topics
- Codon
- Gene Frequency
- Genotype
- Humans
- Lebanon
- Mutation
- Retrospective Studies
- beta-Globins
- beta-Thalassemia