Article
Ki67--An unsuitable marker of gastric cancer prognosis unmasks intratumoral heterogeneity.
Journal of surgical oncology - 1 Jan 2016
Böger Christine, Behrens Hans-Michael, Röcken Christoph
Abstract excerpt
BACKGROUND AND OBJECTIVES: Due to contradictious findings of previous studies regarding Ki67's value in gastric cancer (GC), we reevaluated the expression of Ki67 in whole tissue sections (WTS) and tissue microarrays (TMAs) of GC testing the following hypotheses: does Ki67 show intratumoral heterogeneity; are TMAs representative in the determination of the Ki67 proliferation index (PI); is the Ki67 PI subject to...
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