Article
[Mechanism of c-MET in Non-small Cell Lung Cancer and Its Treatment and Testing].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Dec 2015
Liang Hongge, Wang Mengzhao
Abstract excerpt
Hepatocyte growth factor/c-MET (HGF/c-MET) signaling pathway can be abnormal activated by many mechanisms such as c-MET mutation, amplification and the overexpression of HGF, and it plays an important role in the development of non-small cell lung cancer (NSCLC), as well as in the tolerance of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) in NSCLC. Therefore, c-MET is a new molecular...
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