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Detection of feline coronavirus spike gene mutations as a tool to diagnose feline infectious peritonitis.

Journal of feline medicine and surgery - 1 Apr 2017

Felten Sandra, Weider Karola, Doenges Stephanie, Gruendl Stefanie, Matiasek Kaspar, Hermanns Walter, Mueller Elisabeth, Matiasek Lara, Fischer Andrea, Weber Karin, Hirschberger Johannes, Wess Gerhard, Hartmann Katrin

Abstract excerpt

Objectives Feline infectious peritonitis (FIP) is an important cause of death in the cat population worldwide. The ante-mortem diagnosis of FIP in clinical cases is still challenging. In cats without effusion, a definitive diagnosis can only be achieved post mortem or with invasive methods. The aim of this study was to evaluate the use of a combined reverse transcriptase nested polymerase chain reaction (RT-nPCR)...

Topics

Animals
Base Sequence
Case-Control Studies
Cats
Coronavirus, Feline
Feline Infectious Peritonitis
Female
Male
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Viral

Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 26701958
DOI: 10.1177/1098612X15623824
PMCID: PMC11119656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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