Article
Detection of feline coronavirus mutations in paraffin-embedded tissues in cats with feline infectious peritonitis and controls.
Journal of feline medicine and surgery - 1 Feb 2019
Sangl Laura, Matiasek Kaspar, Felten Sandra, Gründl Stefanie, Bergmann Michele, Balzer Hans-Jörg, Pantchev Nikola, Leutenegger Christian M, Hartmann Katrin
Abstract excerpt
OBJECTIVES: The amino acid substitutions M1058L and S1060A in the spike protein of feline coronavirus (FCoV) have been postulated to be responsible for the development of the pathogenic feline infectious peritonitis virus (FIPV), which causes feline infectious peritonitis (FIP). The aim of the following study was to investigate the presence of mutated virus in tissue samples of cats with and without FIP. METHODS:...
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