Article

Identification of within-host deletions in domain 0 of the spike gene of highly pathogenic feline coronavirus type 2 from the United States

2025-07-15

Abstract excerpt

Feline coronavirus (FCoV) is known to gain pathogenicity within-host to cause the lethal disease feline infectious peritonitis (FIP). Most FIP cases are caused by viruses in genotype 1 (FCoV-1) via an ‘internal mutation’ in the spike gene. However, genotype 2 (FCoV-2) has risen to prominence based on the emergence of FCoV-23, a highly pathogenic novel variant from Cyprus that has a deletion in the N-terminus (doma...

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Literature Corpus work: d1ecdd1a-65d3-5a8c-b999-3d2f05d8bd6c
DOI: 10.1101/2025.07.12.664542

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