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Article

Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis.

Veterinary research - 5 Oct 2017

Barker Emily N, Stranieri Angelica, Helps Chris R, Porter Emily L, Davidson Andrew D, Day Michael J, Knowles Toby, Kipar Anja, Tasker Séverine

Abstract excerpt

Feline infectious peritonitis (FIP) is a fatal disease of cats, and a sequela of systemic feline coronavirus (FCoV) infection. Mutations in the viral spike (S) gene have been associated with FCoVs found in tissues from cats with FIP, but not FCoVs found in faeces from healthy cats, and are implicated in monocyte/macrophage tropism and systemic spread. This study was designed to determine whether S gene mutation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Sequence Analysis, DNA

Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 28982390
DOI: 10.1186/s13567-017-0467-9
PMCID: PMC5629788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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