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Article

Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1.

Neuropsychobiology - 1 Jan 2016

Calabrò Marco, Mandelli Laura, Crisafulli Concetta, Sidoti Antonella, Jun Tae-Youn, Lee Soo-Jung, Han Changsu, Patkar Ashwin A, Masand Prakash S, Pae Chi-Un, Serretti Alessandro

Abstract excerpt

BACKGROUND: Bipolar disorder (BPD) is a common and severe mental disorder. The involvement of genetic factors in the pathophysiology of BPD is well known. In the present study, we tested the association of several single-nucleotide polymorphisms (SNPs) within 3 strong candidate genes (CACNA1C, CHRNA7, and MAPK1) with BPD. These genes are involved in monoamine-related pathways, as well as in dendrite development,...

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Source

Identifiers

PMID: 28494468
DOI: 10.1159/000468543

Genes

MAPK1
CHRNA7
CHRNA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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