Article
Neurotrophins role in depressive symptoms and executive function performance: Association analysis of NRN1 gene and its interaction with BDNF gene in a non-clinical sample.
Journal of affective disorders - 15 Mar 2017
Prats C, Arias B, Ortet G, Ibáñez M I, Moya J, Pomarol-Clotet E, Fañanás L, Fatjó-Vilas M
Abstract excerpt
BACKGROUND: Neuritin-1 is a neurotrophic factor involved in synaptic plasticity that has been associated with depressive disorders, schizophrenia and cognitive performance. The study of genotype-phenotype relationships in healthy individuals is a useful framework to investigate the etiology of brain dysfunctions. We therefore aimed to investigate in a non-clinical sample whether NRN1 gene contributes to the...
Topics
- Adult
- Brain-Derived Neurotrophic Factor
- Depression
- Depressive Disorder
- Executive Function
- Female
- Genetic Predisposition to Disease
- Genotype
- Heterozygote
- Humans