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Article

Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation

23 Dec 2015

Abstract excerpt

RATIONALE: Telomerase is a nuclear regulator of telomere elongation with recent reports suggesting a role in regulation of mitochondrial reactive oxygen species. Flow-mediated dilation in patients with cardiovascular disease is dependent on the formation of reactive oxygen species. OBJECTIVE: We examined the hypothesis that telomerase activity modulates microvascular flow-mediated dilation, and loss of telomerase...

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Share to Mesenchymal stem cell research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26699654
DOI: 10.1161/circresaha.115.307918

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