Article
Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jan 2016
Singhal Prabhat K, Sassi Slim, Lan Lan, Au Patrick, Halvorsen Stefan C, Fukumura Dai, Jain Rakesh K, Seed Brian
Abstract excerpt
Analysis of embryonic fibroblasts from GFP reporter mice indicates that the fibroblast cell type harbors a large collection of developmentally and phenotypically heterogeneous subtypes. Some of these cells exhibit multipotency, whereas others do not. Multiparameter flow cytometry analysis shows that a large number of distinct populations of fibroblast-like cells can be found in cultures initiated from different...
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