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Article

ADAR1, inosine and the immune sensing system: distinguishing self from non-self.

Wiley interdisciplinary reviews. RNA - 1 Jan 2000

Liddicoat Brian J, Chalk Alistair M, Walkley Carl R

Abstract excerpt

The conversion of genomically encoded adenosine to inosine in dsRNA is termed as A-to-I RNA editing. This process is catalyzed by two of the three mammalian ADAR proteins (ADAR1 and ADAR2) both of which have essential functions for normal organismal homeostasis. The phenotype of ADAR2 deficiency can be primarily ascribed to a lack of site-selective editing of a single transcript in the brain. In contrast, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26692549
DOI: 10.1002/wrna.1322

Genes

ADAR
MAVS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ADAR1, inosine and the immune sensing system: distinguishing self from non-self.PMID 26692549Read ↗

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