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Article

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

Genome biology - 5 Sept 2017

Heraud-Farlow Jacki E, Chalk Alistair M, Linder Sandra E, Li Qin, Taylor Scott, White Joshua M, Pang Lokman, Liddicoat Brian J, Gupte Ankita, Li Jin Billy, Walkley Carl R

Abstract excerpt

BACKGROUND: Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein recoding is the essential function of ADAR2, but an essential role for recoding by ADAR1 has not been demonstrated. ADAR1 has been proposed to have...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Immunity, Innate

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Share to Interferon-Induced Helicase, IFIH1

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Source

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Identifiers

PMID: 28874170
DOI: 10.1186/s13059-017-1301-4
PMCID: PMC5585977

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.PMID 28874170Read ↗

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