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Article

Epigenetics and Childhood Asthma: Current Evidence and Future Research Directions

1 Aug 2012

Abstract excerpt

Asthma is the most common chronic disease of childhood, affecting one in eight children in the USA and worldwide. It is a complex disease, influenced by both environmental exposures and genetic factors. Although epigenetic modifications (DNA methylation, histone modification and miRNA) can affect transcriptional activity in multiple genetic pathways relevant for asthma development, very limited work has been...

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PMID: 22920181
DOI: 10.2217/epi.12.32

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