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Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions

22 Jan 2018

Abstract excerpt

We previously found that therapeutic targetable fusions are detected across various cancers. To identify therapeutic targetable fusion in uterine cervical cancer, for which no effective gene targeted therapy has yet been clinically applied, we analyzed RNA sequencing data from 306 cervical cancer samples. We detected 445 high confidence fusion transcripts and identified four samples that harbored FGFR3-TACC3...

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PMID: 29358619
DOI: 10.1038/s41389-017-0018-2

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