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Article

Histone H2AX and the small RNA pathway modulate both non-homologous end-joining and homologous recombination in plants.

Mutation research - 1 Jan 2016

Qi Yiping, Zhang Yong, Baller Joshua A, Voytas Daniel F

Abstract excerpt

Using a zinc finger nuclease (ZFN) that creates a site-specific DNA double-strand break (DSB) at the endogenous ADH1 locus, we provide genetic evidence that histone H2AX and DSB-induced small RNAs modulate DNA repair by both non-homologous end-joining (NHEJ) and homologous recombination (HR) in the model plant Arabidopsis thaliana.

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Source

Identifiers

PMID: 26687994
DOI: 10.1016/j.mrfmmm.2015.12.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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