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Article

Whole-Exome Sequencing in Nine Monozygotic Discordant Twins.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Feb 2016

Zhang Rong, Thiele Holger, Bartmann Peter, Hilger Alina C, Berg Christoph, Herberg Ulrike, Klingmüller Dietrich, Nürnberg Peter, Ludwig Michael, Reutter Heiko

Abstract excerpt

By definition, monozygotic (MZ) twins carry an identical set of genetic information. The observation of early post-twinning mutational events was shown to cause phenotypic discordance among MZ twin pairs. These mutational events comprise genomic alterations at different scales, ranging from single nucleotide changes to larger copy-number variations (CNVs) of varying sizes, as well as epigenetic changes. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Heart Defects, Congenital

Share to Hernias, Diaphragmatic, Congenital

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Source

Identifiers

PMID: 26681452
DOI: 10.1017/thg.2015.93

Genes

TMPRSS13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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