Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional landscape of genome-wide postzygotic somatic mutations between monozygotic twins.

DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Oct 2024

Yamamoto Kenichi, Lee Yoko, Masuda Tatsuo, Ozono Keiichi, Iwatani Yoshinori, Watanabe Mikio, Okada Yukinori, Sakai Norio

Abstract excerpt

Monozygotic (MZ) twins originate from a single fertilized egg, making them genetically identical at the time of conception. However, postzygotic somatic mutations (PZMs) can introduce genetic differences after separation. Although whole-genome sequencing (WGS) sheds light on somatic mutations in cancer genomics, its application in genomic studies of MZ twins remains limited. In this study, we investigate PZMs in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Mutation

Share to Twins, Monozygotic

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 39306676
DOI: 10.1093/dnares/dsae028
PMCID: PMC11472055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional landscape of genome-wide postzygotic somatic mutations between monozygotic twins.PMID 39306676Read ↗

A characterization of postzygotic mutations identified in monozygotic twins.Semantic proximity Read ↗

Common postzygotic mutational signature in multiple healthy adult tissues related to embryonic hypoxiaSemantic proximity Read ↗

Early postzygotic mutations contribute to de novo variation in a healthy monozygotic twin pair.Semantic proximity Read ↗

The origins and functional effects of postzygotic mutations throughout the human lifespanSemantic proximity Read ↗

Landscape of parental postzygotic mutations in >11,000 rare disease triosSemantic proximity Read ↗

Somatic point mutations occurring early in development: a monozygotic twin study.Semantic proximity Read ↗

The origins and functional effects of postzygotic mutations throughout the human life span.Semantic proximity Read ↗

Landscape of parental postzygotic mutations across >11,000 rare disease trios.Semantic proximity Read ↗

Common Postzygotic Mutational Signatures in Healthy Adult Tissues Related to Embryonic Hypoxia.Semantic proximity Read ↗

Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organsSemantic proximity Read ↗

Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs.Semantic proximity Read ↗

Differences between germline genomes of monozygotic twins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.