Article
Whole exome sequencing analysis of ABCC8 and ABCD2 genes associating with clinical course of breast carcinoma.
Physiological research - 1 Jan 2015
Soucek P, Hlavac V, Elsnerova K, Vaclavikova R, Kozevnikovova R, Raus K
Abstract excerpt
The aim of the present study was to introduce methods for exome sequencing of two ATP-binding cassette (ABC) transporters ABCC8 and ABCD2 recently suggested to play a putative role in breast cancer progression and prognosis of patients. We performed next generation sequencing targeted at analysis of all exons in ABCC8 and ABCD2 genes and surrounding noncoding sequences in blood DNA samples from 24 patients with...
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