Article

Inhibition of EV71 replication by an interferon-stimulated gene product L3HYPDH

2018-04-19

Abstract excerpt

Enterovirus 71 (EV71) is the common causative agent of hand-foot-mouth disease (HFMD). Despite evidence in mice model suggested that the interferon (IFN) signaling pathways play a role in defending against this virus, knowledge on the IFN-mediated antiviral response is still limited. Here we identified an IFN-stimulated gene (ISG) called L3HYPHD, whose expression inhibits EV71 replication. Mapping assay indicated...

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Literature Corpus work: 90e58dad-91b5-51e8-a88c-adbbef6a057e
DOI: 10.1101/304345

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