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Destabilization of the gut microbiome marks the end‐stage of simian immunodeficiency virus infection in wild chimpanzees

16 Dec 2015

Abstract excerpt

Enteric dysbiosis is a characteristic feature of progressive human immunodeficiency virus type 1 (HIV‐1) infection but has not been observed in simian immunodeficiency virus (SIVmac)‐infected macaques, including in animals with end‐stage disease. This has raised questions concerning the mechanisms underlying the HIV‐1 associated enteropathy, with factors other than virus infection, such as lifestyle and...

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PMID: 26676710
DOI: 10.1002/ajp.22515

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