Article
Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome.
Cell host & microbe - 9 Mar 2016
Monaco Cynthia L, Gootenberg David B, Zhao Guoyan, Handley Scott A, Ghebremichael Musie S, Lim Efrem S, Lankowski Alex, Baldridge Megan T, Wilen Craig B, Flagg Meaghan, Norman Jason M, Keller Brian C, Luévano Jesús Mario, Wang David, Boum Yap, Martin Jeffrey N, Hunt Peter W, Bangsberg David R, Siedner Mark J, Kwon Douglas S, Virgin Herbert W
Abstract excerpt
Human immunodeficiency virus (HIV) infection is associated with increased intestinal translocation of microbial products and enteropathy as well as alterations in gut bacterial communities. However, whether the enteric virome contributes to this infection and resulting immunodeficiency remains unknown. We characterized the enteric virome and bacterial microbiome in a cohort of Ugandan patients, including...
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