Article

Microbiome Stability with Chronic SIV Infection in AIDS-resistant Sooty Mangabeys

2019-09-24

Abstract excerpt

Sooty mangabeys (SMs) are a natural host species of simian immunodeficiency virus (SIV) and avoid acquired immune deficiency syndrome (AIDS) despite persistently high viral loads, making them a pivotal research model for HIV pathogenesis. Unlike pathogenic SIV infection of macaque species, or HIV infection of humans, SIV-infected SMs maintain gastrointestinal barrier integrity. Here, we characterize the gastrointe...

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Literature Corpus work: c6ea0eab-7a9c-52f0-9612-d18ddf882dbb
DOI: 10.1101/780825

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