Article
Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion.
Acta neuropathologica communications - 15 Dec 2015
Pages Melanie, Lacroix Ludovic, Tauziede-Espariat Arnault, Castel David, Daudigeos-Dubus Estelle, Ridola Vita, Gilles Sophie, Fina Frederic, Andreiuolo Felipe, Polivka Marc, Lechapt-Zalcman Emmanuele, Puget Stephanie, Boddaert Nathalie, Liu Xiao-Qiong, Bridge Julia A, Grill Jacques, Chretien Fabrice, Varlet Pascale
Abstract excerpt
INTRODUCTION: Papillary Glioneuronal Tumor (PGNT) is a grade I tumor which was classified as a separate entity in the World Health Organization Classification of the Central Nervous System 2007 in the group of mixed glioneuronal tumors. This tumor is rare and subclassifying PGNT represents a challenge. Recently, a fusion between SLC44A1 and PRKCA which encodes a protein kinase C involved in MAPK signaling pathway...
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