Article
MAPK pathway alterations in polymorphous low-grade neuroepithelial tumor of the young: diagnostic considerations.
Brain tumor pathology - 1 Oct 2024
Rao Shilpa, Goyal Aditi, Johnson Allen, Sadashiva Nishanth, Kulanthaivelu Karthik, Vazhayil Vikas, Santosh Vani
Abstract excerpt
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognised tumor type with indolent behaviour with characteristic imaging and histomolecular features. We describe the clinical, imaging, histo-molecular features of 15 cases diagnosed as low-grade glioma suggestive of PLNTY, over a period of 3 years. Immunohistochemistry (IHC) and fluorescence in situ hybridisation were used to...
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