Article
The c.64_80del SMIM1 allele is segregating in the Hutterite population.
Transfusion - 1 Apr 2016
Coghlan Gail, Zelinski Teresa
Abstract excerpt
BACKGROUND: The high-incidence red blood cell (RBC) antigen Vel is coded by SMIM1 (small-membrane molecule 1 gene), where a homozygous 17 base pair deletion underlies the majority of Vel- phenotypes. Because anti-Vel has been reported to cause severe hemolytic transfusion reactions and periodically hemolytic disease of the newborn and fetus, identification of individuals negative for Vel is clinically important....
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