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Article

Screening for the SMIM1*64_80 del Allele in blood donors in a population from Southern Brazil.

Transfusion medicine (Oxford, England) - 1 Oct 2016

Costa D C, Dezan M, Santos T, Schinaider A A, Schörner E J, Levi J E, Santos-Silva M C

Abstract excerpt

BACKGROUND AND OBJECTIVES: Serological screening for the Vel- phenotype is complex given the large individual variation in the levels of expression of the Vel antigen, and the polyclonal anti-human sera of immunised persons, when available, show heterogeneous reactivity levels. Studies of the SMIM1 gene have enabled the development of several molecular methodologies that will be crucially important for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 27328373
DOI: 10.1111/tme.12328

Genes

SMIM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for the SMIM1*64_80 del Allele in blood donors in a population from Southern Brazil.PMID 27328373Read ↗

Molecular identification of Vel-negative blood donors in a population from southern Brazil.Semantic proximity Read ↗

SMIM1 polymorphisms in a donor population from southeast Brazil and their correlation with VEL expression.Semantic proximity Read ↗

[Molecular screening for Vel- blood type and analysis of SMIM1 gene variants].Semantic proximity Read ↗

Impact of genetic variation in the SMIM1 gene on Vel expression levels.Semantic proximity Read ↗

Disruption of SMIM1 causes the Vel- blood type.Semantic proximity Read ↗

Homozygosity for a null allele of SMIM1 defines the Vel-negative blood group phenotype.Semantic proximity Read ↗

Beyond the rare blood group Vel, uncovering the functions of SMIM1 in blood and in other organsSemantic proximity Read ↗

The c.64_80del SMIM1 allele is segregating in the Hutterite population.Semantic proximity Read ↗

SMIM1 variants rs1175550 and rs143702418 independently modulate Vel blood group antigen expression.Semantic proximity Read ↗

SMIM1 underlies the Vel blood group and influences red blood cell traits.Semantic proximity Read ↗

SMIM1 missense mutations exert their effect on wild type Vel expression late in erythroid differentiation.Semantic proximity Read ↗

Dimerization of small integral membrane protein 1 promotes cell surface presentation of the Vel blood group epitope.Semantic proximity Read ↗

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