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Article

NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice.

Hepatology (Baltimore, Md.) - 1 Mar 2016

Tosello-Trampont Annie-Carole, Krueger Peter, Narayanan Sowmya, Landes Susan G, Leitinger Norbert, Hahn Young S

Abstract excerpt

UNLABELLED: Nonalcoholic steatohepatitis (NASH) affects 3%-5% of the U.S. population, having severe clinical complications to the development of fibrosis and end-stage liver diseases, such as cirrhosis and hepatocellular carcinoma. A critical cause of NASH is chronic systemic inflammation promoted by innate immune cells, such as liver macrophages (Mϕ) and natural killer (NK) cells. However, little is known about...

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Source

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Identifiers

PMID: 26662852
DOI: 10.1002/hep.28389
PMCID: PMC4764418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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