Article
Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians.
PloS one - 1 Jan 2015
Barsova Rosa M, Lvovs Dmitrijs, Titov Boris V, Matveeva Natalia A, Shakhnovich Roman M, Sukhinina Tatiana S, Kukava Nino G, Ruda Mikhail Ya, Karamova Irina M, Nasibullin Timur R, Mustafina Olga E, Osmak German J, Tsareva Ekaterina Yu, Kulakova Olga G, Favorov Alexander V, Favorova Olga O
Abstract excerpt
BACKGROUND: In spite of progress in cardiovascular genetics, data on genetic background of myocardial infarction are still limited and contradictory. This applies as well to the genes involved in inflammation and coagulation processes, which play a crucial role in the disease etiopathogenesis. METHODS AND RESULTS: In this study we found genetic variants of TGFB1, FGB and CRP genes associated with myocardial...
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