Article
Transient receptor potential channel C5 in cancer chemoresistance.
Acta pharmacologica Sinica - 1 Jan 2016
He Dong-xu, Ma Xin
Abstract excerpt
The transient receptor potential (TRP) superfamily contains at least 28 homologs in mammalian. These proteins form TRP channels are permeable to monovalent and divalent cations and participate in a variety of physiological functions. Dysregulation of TRP channels is responsible for numerous diseases. This review provides a brief short overview of mammalian TRP channels with a focus on TRPC5 and its role in...
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