Article
The transient receptor potential superfamily of ion channels.
Journal of the American Society of Nephrology : JASN - 1 Jul 2004
Huang Chou-Long
Abstract excerpt
ABSTRACT. The transient receptor potential (TRP) superfamily of proteins is cation-selective ion channels with six predicted transmembrane segments and intracellularly localized amino and carboxyl termini. Members of the TRP superfamily are identified on the basis of amino acid sequence and structural similarity and are classified into TRPC, TRPV, TRPM, TRPP, TRPN, and TRPML subfamilies. TRP channels are...
Topics
- Animals
- Biological Transport
- Cations
- Cell Division
- Humans
- Ion Channels
- Kidney Diseases
- Magnesium
- Multigene Family
- Mutation
- Phylogeny
- Protein Structure, Tertiary