Article
DNA microarray-based solid-phase PCR on copoly (DMA-NAS-MAPS) silicon coated slides: An example of relevant clinical application.
Biosensors & bioelectronics - 15 Apr 2016
Damin Francesco, Galbiati Silvia, Ferrari Maurizio, Chiari Marcella
Abstract excerpt
In a previous study we developed a highly sensitive DNA microarray for the detection of common KRAS oncogenic mutations, which has been proven to be highly specific in assigning the correct genotype without any enrichment strategy even in the presence of minority mutated alleles. However, in this approach, the need of a spotter for the deposition of the purified PCR products on the substrates and the purification...
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