Article
The Caenorhabditis elegans Ephrin EFN-4 Functions Non-cell Autonomously with Heparan Sulfate Proteoglycans to Promote Axon Outgrowth and Branching.
Genetics - 1 Feb 2016
Schwieterman Alicia A, Steves Alyse N, Yee Vivian, Donelson Cory J, Bentley Melissa R, Santorella Elise M, Mehlenbacher Taylor V, Pital Aaron, Howard Austin M, Wilson Melissa R, Ereddia Danielle E, Effrein Kelsie S, McMurry Jonathan L, Ackley Brian D, Chisholm Andrew D, Hudson Martin L
Abstract excerpt
The Eph receptors and their cognate ephrin ligands play key roles in many aspects of nervous system development. These interactions typically occur within an individual tissue type, serving either to guide axons to their terminal targets or to define boundaries between the rhombomeres of the hindbrain. We have identified a novel role for the Caenorhabditis elegans ephrin EFN-4 in promoting primary neurite...
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