Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non-Muscle-Invasive Bladder Cancer: A Gene-Smoking Interaction.

doi:10.1158/1940-6207.CAPR-15-0069

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non-Muscle-Invasive Bladder Cancer: A Gene-Smoking Interaction.

Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2016

Lacombe Louis, Fradet Vincent, Lévesque Éric, Pouliot Frédéric, Larue Hélène, Bergeron Alain, Hovington Hélène, Caron André, Nguile-Makao Molière, Harvey Mario, Fradet Yves, Guillemette Chantal

Abstract excerpt

Cigarette smoking is the most important known risk factor for urinary bladder cancer. Selected arylamines in cigarette smoke are recognized human bladder carcinogens and undergo biotransformation through several detoxification pathways, such as the glutathione S-transferases (GST), and uridine-diphospho-glucuronosyltransferases (UGT) pathways. GSTM1 deletion status and UGT1A1*28 rs8175347 genotypes were assessed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Glutathione Transferase

Share to Neoplasm Grading

Share to Neoplasm Invasiveness

Share to Neoplasm Recurrence, Local

Share to Survival Rate

Share to Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 26645279
DOI: 10.1158/1940-6207.CAPR-15-0069

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phase II Drug-Metabolizing Polymorphisms and Smoking Predict Recurrence of Non-Muscle-Invasive Bladder Cancer: A Gene-Smoking Interaction.PMID 26645279Read ↗

Impact of Occupational Exposures and Genetic Polymorphisms on Recurrence and Progression of Non-Muscle-Invasive Bladder Cancer.Semantic proximity Read ↗

Genetic Variations in Glutathione Pathway Genes Predict Cancer Recurrence in Patients Treated with Transurethral Resection and Bacillus Calmette-Guerin Instillation for Non-muscle Invasive Bladder Cancer.Semantic proximity Read ↗

GSTT1 as a prognosticator for recurrence and progression in patients with non-muscle-invasive bladder cancer.Semantic proximity Read ↗

Polymorphisms in drug-metabolizing genes and urinary bladder cancer susceptibility and prognosis: Possible impacts and future management.Semantic proximity Read ↗

GSTM1 tissue genotype as a recurrence predictor in non-muscle invasive bladder cancer.Semantic proximity Read ↗

Genetic variations in micro-RNA biogenesis genes and clinical outcomes in non-muscle-invasive bladder cancer.Semantic proximity Read ↗

Glutathione S-transferase M1 and T1 polymorphisms: susceptibility and outcomes in muscle invasive bladder cancer patients.Semantic proximity Read ↗

AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility.Semantic proximity Read ↗

Epidemiology of urinary bladder cancer: from tumor development to patient's death.Semantic proximity Read ↗

Do smoking and polymorphisms in xenobiotic metabolizing enzymes affect the histological stage and grade of bladder tumors?Semantic proximity Read ↗

GSTA1, GSTM1, GSTP1, and GSTT1 polymorphisms and susceptibility to smoking-related bladder cancer: a case-control study.Semantic proximity Read ↗

Comprehensive genome-wide association study into multiple recurrence and progression risk in non-muscle invasive bladder cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.