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Article

Distribution of mutational fitness effects and of epistasis in the 5' untranslated region of a plant RNA virus.

BMC evolutionary biology - 7 Dec 2015

Bernet Guillermo P, Elena Santiago F

Abstract excerpt

BACKGROUND: Understanding the causes and consequences of phenotypic variability is a central topic of evolutionary biology. Mutations within non-coding cis-regulatory regions are thought to be of major effect since they affect the expression of downstream genes. To address the evolutionary potential of mutations affecting such regions in RNA viruses, we explored the fitness properties of mutations affecting the...

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Identifiers

PMID: 26643527
DOI: 10.1186/s12862-015-0555-2
PMCID: PMC4672503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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