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Article

Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations.

Scientific reports - 9 Apr 2014

Sardanyés Josep, Simó Carles, Martínez Regina, Solé Ricard V, Elena Santiago F

Abstract excerpt

The distribution of mutational fitness effects (DMFE) is crucial to the evolutionary fate of quasispecies. In this article we analyze the effect of the DMFE on the dynamics of a large quasispecies by means of a phenotypic version of the classic Eigen's model that incorporates beneficial, neutral,...

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Identifiers

PMID: 24713667
DOI: 10.1038/srep04625
PMCID: PMC3980229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24713667-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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