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Article

Bone marrow PMN-MDSCs and neutrophils are functionally similar in protection of multiple myeloma from chemotherapy.

Cancer letters - 1 Feb 2016

Ramachandran Indu R, Condamine Thomas, Lin Cindy, Herlihy Sarah E, Garfall Alfred, Vogl Dan T, Gabrilovich Dmitry I, Nefedova Yulia

Abstract excerpt

Multiple myeloma (MM) is an incurable cancer of plasma cells localized preferentially in the bone marrow (BM). Resistance to chemotherapy represents one of the main challenges in MM management. BM microenvironment is known to play a critical role in protection of MM cells from chemotherapeutics; however, mechanisms responsible for this effect are largely unknown. Development of MM is associated with accumulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26639197
DOI: 10.1016/j.canlet.2015.10.040
PMCID: PMC4919899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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