Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis.

doi:10.1007/s12035-015-9559-6

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Article

Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis.

Molecular neurobiology - 1 Dec 2016

Li Ming, Huang Liang, Grigoroiu-Serbanescu Maria, Bergen Sarah E, Landén Mikael, Hultman Christina M, Forstner Andreas J, Strohmaier Jana, Hecker Julian, Schulze Thomas G, Müller-Myhsok Bertram, Reif Andreas, Mitchell Philip B, Martin Nicholas G, Cichon Sven, Nöthen Markus M, Alkelai Anna, Lerer Bernard, Jamain Stéphane, Leboyer Marion, Bellivier Frank, Etain Bruno, Kahn Jean-Pierre, Henry Chantal, Rietschel Marcella

Abstract excerpt

Reelin (RELN) is identified as a risk gene for major psychiatric disorders such as schizophrenia (SCZ) and bipolar disorder (BPD). However, the role of its downstream signaling molecule, the low-density lipoprotein receptor-related protein 8 (LRP8) in these illnesses is still unclear. To detect whether LRP8 is a susceptibility gene for SCZ and BPD, we analyzed the associations of single nucleotide polymorphisms...

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Identifiers

PMID: 26637325
DOI: 10.1007/s12035-015-9559-6

Genes

LRP8
RELN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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